Selected Publication list

​Research articles

1. Schwindt, E. & Paeschke, K. Mms1 is an assistant for regulating G-quadruplex DNA structures. Curr Genet, doi:10.1007/s00294-017-0773-9 (2017).
2. Stinus, S., Paeschke, K. & Chang, M. Telomerase regulation by the Pif1 helicase: a length-dependent effect? Curr Genet, doi:10.1007/s00294-017-0768-6 (2017).
3. Wanzek, K., Schwindt, E., Capra, J. A. & Paeschke, K. Mms1 binds to G-rich regions in Saccharomyces cerevisiae and influences replication and genome stability. Nucleic acids research 45, 7796-7806, doi:10.1093/nar/gkx467 (2017).
4. Kazemier, H. G., Paeschke, K. & Lansdorp, P. M. Guanine quadruplex monoclonal antibody 1H6 cross-reacts with restrained thymidine-rich single stranded DNA. Nucleic acids research 45, 5913-5919, doi:10.1093/nar/gkx245 (2017).
5. Benhalevy, D. et al. The Human CCHC-type Zinc Finger Nucleic Acid-Binding Protein Binds G-Rich Elements in Target mRNA Coding Sequences and Promotes Translation. Cell reports 18, 2979-2990, doi:10.1016/j.celrep.2017.02.080 (2017).
6. Phillips, J. A., Chan, A., Paeschke, K. & Zakian, V. A. The pif1 helicase, a negative regulator of telomerase, acts preferentially at long telomeres. PLoS genetics 11, e1005186, doi:10.1371/journal.pgen.1005186 (2015).
7. Bochman, M. L., Paeschke, K., Chan, A. & Zakian, V. A. Hrq1, a homolog of the human RecQ4 helicase, acts catalytically and structurally to promote genome integrity. Cell reports 6, 346-356, doi:10.1016/j.celrep.2013.12.037 (2014).
8. Paeschke, K. et al. Pif1 family helicases suppress genome instability at G-quadruplex motifs. Nature 497, 458-462, doi:10.1038/nature12149 (2013).​

Reviews

1. Sauer, M. & Paeschke, K. G-quadruplex unwinding helicases and their function in vivo. Biochem Soc Trans 45, 1173-1182, doi:10.1042/BST20170097 (2017).
2. Bochman, M. L., Paeschke, K. & Zakian, V. A. DNA secondary structures: stability and function of G-quadruplex structures. Nature reviews. Genetics 13, 770-780, doi:10.1038/nrg3296 (2012).
3. Juranek, S. A. & Paeschke, K. Cell cycle regulation of G-quadruplex DNA structures at telomeres. Curr Pharm Des 18, 1867-1872 (2012).