Selected Publication list

​Research articles

  1. De Magis, A., Kastl, M., Brossart, P., Heine, A. & Paeschke, K. BG-Flow, a New Flow Cytometry Tool for G-Quadruplex Quantification in Fixed Cells. BMC Biology, (2021).​
  2. Gurung P., Gomes A., Martins R., Juranek S., Alberti P., Mbang-Benet D., Urbach S., Gazanion E., Guitard V., Paeschke K., Lopez-Rubio J. (2020) PfGBP2 is a novel G-quadruplex binding protein in Plasmodium falciparum Cell Microbiol. Doi:10.1111/cmi.13303​
  3. Zacheja T#, Toth A#, Haram Gi, Yang Q, Schwindt E, Kovács M, Paeschke K*, Peter Burkovics* (2020) Mgs1 protein supports genome stability via recognition of G quadruplex DNA structures FASEB J
  4. DeMagis A, Götz S, Hajikazemi M, Fekete-Szücs E, Caterino M, Juranek S.A. Paeschke K (2020) Zuo1 supports G4 structure formation and directs repair towards nucleotide excision repair. Nature Communications, 2020
  5. Zacheja T*, Toth A*, Haram Gi, Yang Q, Schwindt E, Kovács M, Paeschke K*, Peter Burkovics*, Mgs1 protein supports genome stability via recognition of G quadruplex DNA structures FASEB J, 2020 
  6. Jurkikova*, Garjarsky*, Hajikzemi*et al , JBC, 2020, May 8th
  7. Rosenbaum JC1, Bonilla B2, Hengel SR2, Mertz TM3, Herken BW2, Kazemier HG4, Pressimone CA2, Ratterman TC5, MacNary E3, De Magis A6, Kwon Y7,8, Godin SK2, Van Houten B9, Normolle DP10, Sung P7,8, Das SR5, Paeschke K4,6, Roberts SA3, VanDemark AP1, Bernstein KA11. Nat Commun. 2019 Aug 5;10(1):3515. doi: 10.1038/s41467-019-11374-8.(2019)
  8. Sauer M, Juranek SA, Marks J, De Magis A, Kazemier HG, Hilbig D, Benhalevy D, Wang X, Hafner M, Paeschke K. DHX36 prevents the accumulation of translationally inactive mRNAs with G4-structures in untranslated regions  Nat Commun. 2019 Jun 3;10(1):2421. doi: 10.1038/s41467-019-10432-5 (2019)
  9. Goetz, Pandey, Barts, Juranek, Paeschke A Novel G-Quadruplex Binding Protein in Yeast-Slx9 Molecules. 2019 May 7;24(9). pii: E1774. doi: 10.3390/molecules24091774 (2019)
  10. Schwindt, E. & Paeschke, K. Mms1 is an assistant for regulating G-quadruplex DNA structures. Curr Genet, doi:10.1007/s00294-017-0773-9 (2017).
  11. Stinus, S., Paeschke, K. & Chang, M. Telomerase regulation by the Pif1 helicase: a length-dependent effect? Curr Genet, doi:10.1007/s00294-017-0768-6 (2017).
  12. Wanzek, K., Schwindt, E., Capra, J. A. & Paeschke, K. Mms1 binds to G-rich regions in Saccharomyces cerevisiae and influences replication and genome stability. Nucleic acids research 45, 7796-7806, doi:10.1093/nar/gkx467 (2017).
  13. Kazemier, H. G., Paeschke, K*. & Lansdorp, P. M*. Guanine quadruplex monoclonal antibody 1H6 cross-reacts with restrained thymidine-rich single stranded DNA. Nucleic acids research 45, 5913-5919, doi:10.1093/nar/gkx245 (2017).
  14. Benhalevy, D. et al. The Human CCHC-type Zinc Finger Nucleic Acid-Binding Protein Binds G-Rich Elements in Target mRNA Coding Sequences and Promotes Translation. Cell reports 18, 2979-2990, doi:10.1016/j.celrep.2017.02.080 (2017).
  15. Phillips, J. A., Chan, A., Paeschke, K. & Zakian, V. A. The pif1 helicase, a negative regulator of telomerase, acts preferentially at long telomeres. PLoS genetics 11, e1005186, doi:10.1371/journal.pgen.1005186 (2015).
  16. Bochman, M. L., Paeschke, K., Chan, A. & Zakian, V. A. Hrq1, a homolog of the human RecQ4 helicase, acts catalytically and structurally to promote genome integrity. Cell reports 6, 346-356, doi:10.1016/j.celrep.2013.12.037 (2014).
  17. Paeschke, K. et al. Pif1 family helicases suppress genome instability at G-quadruplex motifs. Nature 497, 458-462, doi:10.1038/nature12149 (2013).​

Reviews

    ​
  1. Kosiol N., Juranek S, Brossart P, Heine A, Paeschke K, G-quadruplexes: A Promising Target for Cancer Therapy, Molecular Cancer (2021)
  2. Paeschke K*, Burkovics P.* (2020) Mgs1 function and role at G-quadruplex structures during DNA replicationCurrent Genetics
  3. Schult P., Paeschke K* (2020) The DEAH helicase DHX36 and its role in G-quadruplex-dependent processes. doi: 10.1515/hsz-2020-0292. Biol Chem
  4. Sauer, M. & Paeschke, K. G-quadruplex unwinding helicases and their function in vivo. Biochem Soc Trans 45, 1173-1182, doi:10.1042/BST20170097 (2017).
  5. Bochman, M. L., Paeschke, K. & Zakian, V. A. DNA secondary structures: stability and function of G-quadruplex structures. Nature reviews. Genetics 13, 770-780, doi:10.1038/nrg3296 (2012).
  6. Juranek, S. A. & Paeschke, K. Cell cycle regulation of G-quadruplex DNA structures at telomeres. Curr Pharm Des 18, 1867-1872 (2012).
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