Selected Publication list

​Research articles

1. Sauer M, Juranek SA, Marks J, De Magis A, Kazemier HG, Hilbig D, Benhalevy D, Wang X, Hafner M, Paeschke K. DHX36 prevents the accumulation of translationally inactive mRNAs with G4-structures in untranslated regions  Nat Commun. 2019 Jun 3;10(1):2421. doi: 10.1038/s41467-019-10432-5 (2019)
   
2. Goetz, Pandey, Barts, Juranek, Paeschke A Novel G-Quadruplex Binding Protein in Yeast-Slx9 Molecules. 2019 May 7;24(9). pii: E1774. doi: 10.3390/molecules24091774 (2019)
3. Schwindt, E. & Paeschke, K. Mms1 is an assistant for regulating G-quadruplex DNA structures. Curr Genet, doi:10.1007/s00294-017-0773-9 (2017).
4. Stinus, S., Paeschke, K. & Chang, M. Telomerase regulation by the Pif1 helicase: a length-dependent effect? Curr Genet, doi:10.1007/s00294-017-0768-6 (2017).
5. Wanzek, K., Schwindt, E., Capra, J. A. & Paeschke, K. Mms1 binds to G-rich regions in Saccharomyces cerevisiae and influences replication and genome stability. Nucleic acids research 45, 7796-7806, doi:10.1093/nar/gkx467 (2017).
6. Kazemier, H. G., Paeschke, K. & Lansdorp, P. M. Guanine quadruplex monoclonal antibody 1H6 cross-reacts with restrained thymidine-rich single stranded DNA. Nucleic acids research 45, 5913-5919, doi:10.1093/nar/gkx245 (2017).
7. Benhalevy, D. et al. The Human CCHC-type Zinc Finger Nucleic Acid-Binding Protein Binds G-Rich Elements in Target mRNA Coding Sequences and Promotes Translation. Cell reports 18, 2979-2990, doi:10.1016/j.celrep.2017.02.080 (2017).
8. Phillips, J. A., Chan, A., Paeschke, K. & Zakian, V. A. The pif1 helicase, a negative regulator of telomerase, acts preferentially at long telomeres. PLoS genetics 11, e1005186, doi:10.1371/journal.pgen.1005186 (2015).
9. Bochman, M. L., Paeschke, K., Chan, A. & Zakian, V. A. Hrq1, a homolog of the human RecQ4 helicase, acts catalytically and structurally to promote genome integrity. Cell reports 6, 346-356, doi:10.1016/j.celrep.2013.12.037 (2014).
10. Paeschke, K. et al. Pif1 family helicases suppress genome instability at G-quadruplex motifs. Nature 497, 458-462, doi:10.1038/nature12149 (2013).​

Reviews

1. Sauer, M. & Paeschke, K. G-quadruplex unwinding helicases and their function in vivo. Biochem Soc Trans 45, 1173-1182, doi:10.1042/BST20170097 (2017).
2. Bochman, M. L., Paeschke, K. & Zakian, V. A. DNA secondary structures: stability and function of G-quadruplex structures. Nature reviews. Genetics 13, 770-780, doi:10.1038/nrg3296 (2012).
3. Juranek, S. A. & Paeschke, K. Cell cycle regulation of G-quadruplex DNA structures at telomeres. Curr Pharm Des 18, 1867-1872 (2012).